Verification of reagent lot to lot is considered part of good laboratory practices and in many accreditation standards such procedures are required / mandated prior to the use of a new lot of reagent.As with each new lot of reagent there is always a potential where quality control materials and/or patient sample performance may be impacted. There is a multitude of factors that can affect the performance of a new reagent lot which may include critical changes or updates in the reagent formulation from manufacturers, decreased stability of reagents either due to temperature excursions during transportation and storage or even handling errors to name a few.

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